CodeLite IDE

It seems, I have to change WXCFG enviroment variable from WXCFG=gcc_lib\mswud to WXCFG=gcc_lib\mswu,
when I change projekt configuration from Debug to Release or vice versa - is there a strategy avoiding the need
to keep WXCFG enviroment variable syncronized with the choosen projekt configuration?

You can set it per build configuration.
Project settings->Common Settings->Environment

This field is per build configuration (i.e. one per Release and one per Debug)

Eran